Thermo Fisher Scientific PIK3R4 Monoclonal Antibody (OTI5D1), TrueMAB
인간 PIK3R4 단백질(aa732-1036)을 항원으로 제작된 Mouse IgG1 단클론 항체로, IHC(P)에서 1:150 희석으로 검증됨. 액상 형태이며 1 mg/mL 농도, PBS/BSA/glycerol 저장 버퍼 포함. PI3K 복합체 조절 단위 연구용에 적합.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5D1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 732–1036 of human PIK3R4 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Regulatory subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate. Different complex forms are believed to play roles in multiple membrane trafficking pathways:
- PI3KC3-C1: involved in initiation of autophagosomes
- PI3KC3-C2: involved in maturation of autophagosomes and endocytosis
Involved in regulation of degradative endocytic trafficking and cytokinesis, probably in the context of PI3KC3-C2 (PubMed:20643123). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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