Thermo Fisher Scientific Kinesin 5B Monoclonal Antibody (KN-03)
Kinesin 5B 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, 인간·마우스·돼지·랫트 반응성. ICC/IF에 적합하며 액상 형태로 1 mg/mL 농도. Taxol 안정화 미세소관 결합 kinesin 인식. 연구용으로만 사용 가능.
- 판매단위
- pk
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Applications
- Immunocytochemistry (ICC/IF)
Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Pig, Rat |
| Host / Isotype | Mouse / IgM |
| Class | Monoclonal |
| Type | Antibody |
| Clone | KN-03 |
| Immunogen | Enriched fraction of porcine brain kinesin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | TBS, pH 8 |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Wet ice |
| RRID | AB_2132395 |
Product Specific Information
This antibody recognizes kinesin bound to taxol-stabilized microtubules.
Target Information
Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes.
Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a ZFYVE27-dependent manner.
Regulates centrosome and nuclear positioning during mitotic entry.
During the G2 phase of the cell cycle in a BICD2-dependent manner, antagonizes dynein function and drives the separation of nuclei and centrosomes.
Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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