Thermo Fisher Scientific HNMT Polyclonal Antibody, MaxPab
Thermo Fisher Scientific의 HNMT Polyclonal Antibody는 인간 HNMT 단백질을 인식하는 토끼 IgG 항체입니다. Western blot에 최적화되어 있으며, PBS 기반의 액상 형태로 제공됩니다. 연구용으로만 사용되며, -20°C에서 보관합니다.
- 카탈로그번호
- H00003176-D01P
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): 1–5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | HNMT (AAH20677.1, 1–292 a.a) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MASSMRSLFS DHGKYVESFR RFLNHSTEHQ CMQEFMDKKL PGIIGRIGDT KSEIKILSIG GGAGEIDLQI LSKVQAQYPG VCINNEVVEP SAEQIAKYKE LVAKTSNLEN VKFAWHKETS SEYQSRMLEK KELQKWDFIH MIQMLYYVKD IPATLKFFHS LLGTNAKMLI IVVSGSSGWD KLWKKYGSRF PQDDLCQYIT SDDLTQMLDN LGLKYECYDL LSTMDISDCF IDGDENGDLL WDFLTETCNF NATAPPDLRA ELGKDLQEPE FSAKKEGKVL FNNTLSFIVI EA
Target Information
In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase (HNMT) and oxidative deamination via diamine oxidase.
HNMT is a cytosolic enzyme that uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, histamine neurotransmission is regulated by N(tau)-methylation since diamine oxidase is absent in the central nervous system.
A common genetic polymorphism affects the activity levels of this gene product in red blood cells.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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