Thermo Fisher Scientific HNRNPA2B1 Monoclonal Antibody (1G12-6C5)

Applications and Tested Dilution

Product Specifications

Product Specific Information

Protein Sequence:

MEREKEQFRK LFIGGLSFET TEESLRNYYE QWGKLTDCVV MRDPASKRSR GFGFVTFSSM AEVDAAMAAR PHSIDGRVVE PKRAVAREES GKPGAHVTVK KLFVGGIKED TEEHHLRDYF EEYGKIDTIE IITDRQSGKK RGFGFVTFDD HDPVDKIVLQ KYHTINGHNA EVRKALSRQE MQEDLEVAIL EVAPVMEEEE EDMVVEDLDM ATRVGATEVV MTTMEEEIME VEITMILEII TSNLLTTVQ

Target Information

This gene belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA-binding proteins that complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and influence pre-mRNA processing, mRNA metabolism, and transport. Although all hnRNPs are nuclear, some shuttle between the nucleus and cytoplasm. The hnRNP proteins have distinct nucleic acid-binding properties. The encoded protein contains two quasi-RRM domains that bind RNAs. Two alternatively spliced transcript variants encoding different isoforms have been described.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.