
Thermo Fisher Scientific HNF4A Monoclonal Antibody (4E2)
HNF4A 단백질을 인식하는 Mouse 모노클론 항체로, Western blot과 ELISA에 적합합니다. 사람 종에 반응하며, 비결합형 액상 형태로 제공됩니다. 간, 신장, 췌장 등에서 발현되는 HNF4A 연구용으로 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Concentration: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4E2 |
| Immunogen | HNF4A (NP_000448.3, 324–423 a.a) partial recombinant protein with GST tag (MW of GST tag = 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
NDRQYDSRGR FGELLLLLPT LQSITWQMIE QIQFIKLFGM AKIDNLLQEM LLGGSPSDAP HAHHPLHPHL MQEHMGTNVI VANTMPTHLS NGQMCEWPRP
Target Information
Hepatocyte nuclear factor 4 alpha (HNF4A) is an orphan nuclear receptor expressed in liver, kidney, intestine, and pancreas.
Mutation of HNF4A in humans has been associated with maturity-onset diabetes of the young type 1 (MODY1).
HNF4 binds to DNA as an exclusive homodimer. The HNF4A gene is alternatively spliced and may generate up to nine different isoforms (HNF4A1 through HNF4A9).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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