Thermo Fisher Scientific HNF4A Monoclonal Antibody (3C6)
HNF4A 단백질을 인식하는 Thermo Fisher Scientific의 Mouse Monoclonal Antibody (Clone 3C6). Western blot, ICC/IF, ELISA에 적합하며 인간 시료에 반응. 고순도 Affinity chromatography 정제, PBS buffer에 보존, 연구용 전용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| ELISA | 0.1 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3C6 |
| Immunogen | HNF4A (NP_000448, 324–423 a.a.) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
NDRQYDSRGR FGELLLLLPT LQSITWQMIE QIQFIKLFGM AKIDNLLQEM LLGGSPSDAP HAHHPLHPHL MQEHMGTNVI VANTMPTHLS NGQMCEWPRP
Target Information
Hepatocyte nuclear factor 4 alpha (HNF4α) is an orphan nuclear receptor expressed in the liver, kidney, intestine, and pancreas. Mutation of HNF4α in humans is associated with maturity-onset diabetes of the young type 1 (MODY1). HNF4 binds to DNA as a homodimer. The HNF4α gene is alternatively spliced and may generate up to nine different isoforms (HNF4α1–HNF4α9).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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