Thermo Fisher Scientific CXCL9 Recombinant Rabbit Monoclonal Antibody (11H1L14)

Applications and Tested Dilution

Product Specifications

Product Specific Information

• Intact IgG appears on a non-reducing gel as ~150 kDa band and upon reduction generates a ~25 kDa light chain band and a ~50 kDa heavy chain.
• Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems developed by cloning specific antibody DNA sequences from immunoreactive rabbits.
• Individual clones are screened to select the best candidates for production.
• Advantages include:
  • Better specificity and sensitivity
  • Lot-to-lot consistency
  • Animal origin-free formulations
  • Broader immunoreactivity to diverse targets due to larger rabbit immune repertoire

Target Information

MIG, also known as CXCL9, is a T-cell chemoattractant inducible by gamma interferon and a member of the CXC chemokine family of cytokines.
This gene is mapped to 4q21. Chemokines act as chemotactic factors and influence T-cell activation, angiogenesis, and HIV infection.
While most CXC chemokines are chemotactic for neutrophils, MIG and INP10 are unique in being chemotactic for lymphocytes and inactive in neutrophils.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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