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Thermo Fisher Scientific Phospho-NFkB-p65 (Ser468) Polyclonal Antibody
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NFkB p65 단백질의 Ser468 인산화 부위를 인식하는 Rabbit Polyclonal 항체로, WB, IHC, IP에 적합합니다. Human 및 Mouse 시료 반응성이 있으며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- 500-11854
- 판매단위
- pk
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마지막 업데이트 2025. 08. 05. 오전 09:52
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Thermo Fisher Scientific 500-11854 Phospho-NFkB-p65 (Ser468) Polyclonal Antibody 100 ug pk판매 단위 pk ·
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Thermo Fisher Scientific · Thermo Fisher Scientific Phospho-NFkB-p65 (Ser468) Polyclonal Antibody
Thermo Fisher Scientific Phospho-NFkB-p65 (Ser468) Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–10 µg/mL |
| Immunoprecipitation (IP) | 2–5 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the epitope containing phosphorylation site Ser468 of human NFkB/p65 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 25 mM Tris with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term; for long-term storage, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: All human tissue
- Cellular location: Nucleus, Cytoplasm
Target Information
Nuclear factor kB p65 (NF-kB p65) is encoded by the RELA gene and located on chromosome 11 in humans. Also known as RelA, it belongs to the Rel family of proteins and forms a heterodimer with p50 or p52 subunits of NF-kB. Upon TNFα stimulation, IKK phosphorylates IκB, leading to its proteasomal degradation. NF-kB p65 plays a key role in transcriptional regulation of the immunoglobulin kappa gene in mature B-lymphoid cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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