Thermo Fisher Scientific CTLA4 Monoclonal Antibody (OTI12C6)
인간 CTLA4 단백질을 인식하는 마우스 단클론 항체로, Flow Cytometry에 적합합니다. 동결건조 형태로 제공되며, PBS와 trehalose로 안정화되었습니다. 재구성 후 약 1 mg/mL 농도로 사용 가능하며, 연구용으로만 사용됩니다.
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Applications
- Flow Cytometry (Flow)
Tested Dilution: 1:400
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI12C6 |
| Immunogen | Full length human recombinant protein of human CTLA4 (NP_005205) produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform desalting using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882) before use.
Target Information
CTLA4 (Cytotoxic T-Lymphocyte Antigen 4) is a CD28-family receptor expressed mainly on CD4+ T cells. It binds the same ligands as CD28 (CD80 and CD86 on B cells and dendritic cells) but with higher affinity. Unlike CD28, which enhances T cell activation, CTLA4 inhibits T cell function. Intracellular CTLA4 is also found in regulatory T cells and may play a key role in their activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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