Thermo Fisher Scientific CTLA4 Monoclonal Antibody (OTI9F3)
인간 CTLA4 단백질을 인식하는 마우스 단클론 항체로, Flow Cytometry에 적합합니다. 무보존제 동결건조 형태이며, 재구성 후 약 1 mg/mL 농도로 사용 가능합니다. CTLA4 기능 연구 및 T세포 억제 기전 분석에 활용됩니다.
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Applications
- Flow Cytometry (Flow): Tested dilution 1:400
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI9F3 |
| Immunogen | Full length human recombinant protein of human CTLA4 (NP_005205) produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
CTLA4 (Cytotoxic T-Lymphocyte Antigen 4) is a CD28-family receptor mainly expressed on CD4+ T cells.
It binds ligands CD80 and CD86 on B cells and dendritic cells with higher affinity than CD28.
Unlike CD28, which enhances T cell activation, CTLA4 inhibits T cell function and contributes to immune regulation.
Intracellular CTLA4 is also present in regulatory T cells, playing an essential role in their suppressive function.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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