Thermo Fisher Scientific SLC7A5 Polyclonal Antibody
SLC7A5 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P)에서 10–20 µg/mL 농도로 사용 가능. Human 및 다양한 종에 반응하며, 항원 친화 크로마토그래피로 정제됨. PBS 기반 용액 형태로 제공되며, 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 10–20 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human, Non-human primate, Rabbit |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 14 amino acid peptide from N-terminus of human SLC7A5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550514 |
Product Specific Information
- Percent identity with other species by BLAST analysis:
Human, Gorilla, Gibbon, Marmoset, Dog, Elephant, Rabbit, Platypus (100%);
Opossum (93%); Mouse, Rat, Bat, Hamster, Panda, Chicken (86%). - For IHC(P), use heat-induced antigen retrieval in pH 6.0 citrate buffer.
After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
Target Information
Solute carrier family 7 member 5 (SLC7A5), also known as large neutral amino acids transporter small subunit 1, is a protein encoded by the SLC7A5 gene in humans.
It mediates sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine, and tryptophan when associated with SLC3A2/4F2hc.
SLC7A5 is involved in cellular amino acid uptake and the transport of L-DOPA across the blood-brain barrier, as well as thyroid hormones (T3, T4) across cell membranes in tissues such as placenta.
It functions as an amino acid exchanger and plays a role in neuronal cell proliferation (neurogenesis) in the brain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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