Thermo Fisher Scientific SLC7A5 Polyclonal Antibody
SLC7A5 단백질을 인식하는 Thermo Fisher Scientific의 토끼 다클론 항체. IHC(P) 검증 완료. 인간 시료에 반응하며, 항원 친화 크로마토그래피로 정제됨. 단백질 발현 연구 및 아미노산 수송 관련 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC(P)) | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 15 amino acid peptide from internal region of human SLC7A5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550513 |
Product Specific Information
- Percent identity with other species by BLAST analysis:
Human, Gibbon (100%); Gorilla, Monkey (93%); Mouse, Rat, Dog, Bat, Panda (80%) - For IHC(P), use heat-induced antigen retrieval in pH 6.0 citrate buffer.
After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
Target Information
Solute carrier family 7 member 5 (SLC7A5), also known as large neutral amino acids transporter small subunit 1, is a protein encoded by the SLC7A5 gene in humans.
It mediates sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine, and tryptophan when associated with SLC3A2/4F2hc.
SLC7A5 is involved in cellular amino acid uptake and transport of L-DOPA across the blood-brain barrier, as well as thyroid hormones (T3, T4) across cell membranes in tissues such as placenta.
It acts as an amino acid exchanger and plays a role in neuronal cell proliferation (neurogenesis) in the brain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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