Thermo Fisher Scientific SLITRK6 Polyclonal Antibody
SLITRK6 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 다양한 종에서 반응하며, IHC(P) 등 연구용으로 적합. 항원 친화 크로마토그래피로 정제된 고품질 항체로 신경 관련 단백질 연구에 활용 가능.
- 카탈로그번호
- PA533054
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific SLITRK6 Polyclonal Antibody
Applications and Tested Dilution
- Immunohistochemistry (Paraffin) [IHC (P)]: 15 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bat, Bovine, Dog, Human, Non-human primate, Pig |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 14 amino acid peptide from internal region of human SLITRK6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550515 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human, Gibbon, Monkey, Marmoset, Dog, Bovine, Bat, Panda, Pig (100%)
Gorilla, Mouse, Hamster, Elephant (93%)
Target Information
SLIT and NTRK-like family 6 (Slitrk6) belongs to a family of six homologous transmembrane proteins (Slitrk1–6) sharing two conserved leucine-rich repeat domains in the extracellular region and significant homology to Slit, a secreted axonal growth-controlling protein. These proteins also show homology to trk neurotrophin receptors in their intracellular domains.
Expression of Slitrk proteins is largely restricted to neural and brain tumor tissues, with Slitrk6 observed in tongue, lung, gastrointestinal tract, and pancreas. Overexpression of Slitrk6 inhibits neurite outgrowth in cultured neurons, suggesting a role in neurite growth regulation. At least two isoforms of Slitrk6 are known to exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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