Thermo Fisher Scientific p21WAF1 (Tumor Suppressor Protein) Recombinant Rabbit Monoclonal Antibody (CIP1, 4377R)
p21WAF1 종양억제 단백질을 인식하는 재조합 토끼 단일클론 항체로, WB 및 IHC에 적합. 인간 반응성, HEK293 발현 시스템 사용. Protein A/G 정제, 보존제 무첨가. 세포 주기 조절 및 DNA 손상 반응 연구에 유용.
✨AI 추천 연관 상품
AI가 분석한 이 상품과 연관된 추천 상품들을 확인해보세요
연관 상품을 찾고 있습니다...
Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 2–4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | CIP1, 4377R |
| Immunogen | Synthetic peptide corresponding to p21 residues within aa1–100 of p21 was used as an immunogen |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Immunohistochemistry (PFA fixed): Incubate antibody for 30 min at room temperature.
Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
Protein p21 is a tumor suppressor protein that inhibits Cyclin-dependent kinases (CDK) and is transcriptionally activated by p53.
It plays a key role in cellular response to genotoxic stress and is a major transcriptional target of p53.
In the nucleus, p21 binds and inhibits Cdk1 and Cdk2, blocking transitions from G1 to S phase or G2 to mitosis after DNA damage, allowing DNA repair.
In the cytoplasm, p21 has anti-apoptotic effects by inhibiting caspase 3 and apoptotic kinases ASK1 and JNK.
P21 exhibits dual roles in carcinogenesis, functioning as both a tumor suppressor and oncogene depending on context.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
🏷️Thermo Fisher Scientific 상품 둘러보기
동일 브랜드의 다른 상품들을 확인해보세요
Thermo Fisher Scientific
Thermo Fisher Scientific p21WAF1 (Tumor Suppressor Protein) Recombinant Rabbit Monoclonal Antibody (CIP1/2275R)
452,600원
Thermo Fisher Scientific
Thermo Fisher Scientific p21WAF1 (Tumor Suppressor Protein) Recombinant Rabbit Monoclonal Antibody (CIP1/2275R)
904,200원
Thermo Fisher Scientific
Thermo Fisher Scientific p21WAF1 (Tumor Suppressor Protein) Recombinant Rabbit Monoclonal Antibody (CIP1, 4377R)
829,000원
Thermo Fisher Scientific
Thermo Fisher Scientific p21WAF1 (Tumor Suppressor Protein) Recombinant Rabbit Monoclonal Antibody (CIP1, 4377R)
443,800원
Thermo Fisher Scientific
Thermo Fisher Scientific p21WAF1 (Tumor Suppressor Protein) Monoclonal Antibody (AC8)
449,700원
배송/결제/교환/반품 안내
배송 정보
| 기본 배송비 |
| 교환/반품 배송비 |
|
|---|---|---|---|
| 착불 배송비 |
| ||
| 교환/반품 배송비 |
| ||
결제 및 환불 안내
| 결제수단 |
|
|---|---|
| 취소 |
|
| 반품 |
|
| 환급 |
|
교환 및 반품 접수
| 교환 및 반품 접수 기한 |
|
|---|---|
| 교환 및 반품 접수가 가능한 경우 |
|
| 교환 및 반품 접수가 불가능한 경우 |
|
교환 및 반품 신청
| 교환 절차 |
|
|---|---|
| 반품 절차 |
|