Thermo Fisher Scientific ErbB2 (HER-2) Monoclonal Antibody (ICR55)
HER2/neu 단백질을 인식하는 Rat monoclonal antibody (clone ICR55). Western blot, IHC, Flow cytometry, IP 등 다양한 응용에 사용 가능. Human 시료 반응성. Protein G 정제, PBS buffer에 0.09% sodium azide 포함. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay-dependent |
| Flow Cytometry (Flow) | Assay-dependent |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rat / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | ICR55 |
| Immunogen | Proprietary Immunogen |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_928560 |
Product Specific Information
For FACS analysis, use 10 µL of the suggested working dilution to label 1×10⁶ cells in 100 µL.
Rat anti-Human HER2/neu antibody, clone ICR55 recognizes epitope E of human HER2/neu (also known as CD340 and c-ErbB-2), a proto-oncogene expressed at the cell surface of various tumor cells. Expression is often associated with poor prognosis and increased metastasis risk.
Target Information
ErbB2 (HER2) is a receptor tyrosine kinase overexpressed in some breast tumors. Herceptin, used in treatment of metastatic HER2-positive cancer, is a monoclonal antibody targeting this kinase.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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