Thermo Fisher Scientific Phospho-GABBR2 (Ser893) Polyclonal Antibody
GABBR2 단백질의 Ser893 인산화 부위를 인식하는 폴리클로날 항체로, Western blot 및 IHC(P)에서 사용 가능. 사람, 마우스, 랫트 반응성. 1 mg/mL 농도의 액상 형태로 제공되며, -20°C에서 보관. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human GABBR2 (Accession O75899), corresponding to amino acid residues around phosphorylated Ser893. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2817486 |
Product Specific Information
This antibody detects endogenous levels of GABBR2 only when phosphorylated at Ser893.
Target Information
The multi-pass membrane protein GABBR2 belongs to the G-protein coupled receptor 3 family and the GABA-B receptor subfamily. GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, regulating neurotransmitter release, ion channel activity, and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, and neither subunit is functional alone. Allelic variants of this gene have been associated with nicotine dependence.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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