Thermo Fisher Scientific SGK1 Polyclonal Antibody
SGK1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(P)에서 사용 가능. Human, Mouse, Rat에 반응하며, 항원 친화 크로마토그래피로 정제됨. 고순도(>95%)의 액상 형태로 1 mg/mL 농도. 세포 스트레스 반응 및 생존 연구에 적합.
- 카탈로그번호
- PA586236
- 판매단위
- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 391–431 of Human SGK1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at −20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2803026 |
Product Specific Information
Purity is >95% by SDS-PAGE.
Target Information
SGK (SGK1) is a serine/threonine kinase that may act as a transcriptional target for p38/MAPK in hepatoma cells. It plays an important role in cellular stress response and cell survival. SGK1 is transcriptionally activated by various stimuli including serum, glucocorticoids, osmotic stress, and hormones. It phosphorylates and negatively regulates the pro-apoptotic protein FOXO3A. SGK1 is considered essential in nephropathy and cardiovascular development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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