
Thermo Fisher Scientific BAD Polyclonal Antibody
BAD 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot 및 IHC(P)에서 검증됨. Human, Mouse, Rat에 반응하며, 항원 친화 크로마토그래피로 정제됨. 고순도(>95%)로 세포사멸 연구에 적합. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 72–126 of Human BAD |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2803022 |
Product Specific Information
Purity is >95% by SDS-PAGE.
Target Information
The protein encoded by BAD is a member of the BCL-2 family, known to regulate programmed cell death. BAD promotes apoptosis by forming heterodimers with BCL-xL and BCL-2, counteracting their anti-apoptotic function. Its proapoptotic activity is regulated via phosphorylation, involving kinases such as AKT and MAP kinase, and phosphatase calcineurin. Alternative splicing generates two transcript variants encoding the same isoform.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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