Thermo Fisher Scientific FGFR2 Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

PA5-29426 targets FGFR2 in WB applications and shows reactivity with Human samples.
The immunogen is a recombinant fragment corresponding to a region within amino acids 539–821 of Human FGFR2.

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
For short-term storage (1–2 weeks), product can be stored at 4°C.
For long-term storage, aliquot and store product at -20°C or below, avoiding multiple freeze-thaw cycles.

Target Information

FGFR2 (Fibroblast Growth Factor Receptor 2) is a member of the FGFR family of receptor tyrosine kinases.
This family regulates various cellular functions including angiogenesis, mitogenesis, osteogenesis, myogenesis, carcinogenesis, cellular differentiation, and tissue repair after injury.

FGFR family members differ in ligand affinities and tissue distribution.
Mutations in FGFR2 are associated with several syndromes such as Crouzon, Pfeiffer, Craniosynostosis, Apert, Jackson-Weiss, Beare-Stevenson cutis gyrata, Saethre-Chotzen, and syndromic craniosynostosis.
Multiple alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.