Thermo Fisher Scientific SFMBT1 Recombinant Human Monoclonal Antibody (RAB-C396)

Applications

Tested Dilution

Publications

ELISA (ELISA)

Assay-dependent

-

ChIP assay (ChIP)

Assay-dependent

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Human / F(ab), kappa

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

RAB-C396

Immunogen

This antibody was obtained by recombinant antibody (rAb) phage display recognizing SFMBT1 protein under non-denaturing conditions.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Metal-chelate chromatography

Storage buffer

PBS

Contains

0.02% ProClin 300

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

Product Specific Information

This antibody recognizes SFMBT1 (Scm-like with four MBT domains protein 1). It binds to a folded domain, amino acids 1-455. SFMBT1 is a histone-binding protein, which is part of various corepressor complexes. It mediates the recruitment of corepressor complexes to target genes, followed by chromatin compaction and repression of transcription and plays a role during myogenesis.

Target Information

This gene shares high similarity with the Drosophila Scm (sex comb on midleg) gene. It encodes a protein which contains four malignant brain tumor repeat (mbt) domains and may be involved in antigen recognition.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.