Thermo Fisher Scientific SFMBT1 Recombinant Human Monoclonal Antibody (RAB-C396)
SFMBT1 단백질을 인식하는 인간 재조합 단일클론 항체로 ELISA 및 ChIP 분석에 적합. HEK293 세포에서 발현된 F(ab) 형태 항체이며, 금속 킬레이트 크로마토그래피로 정제됨. SFMBT1의 핵심 도메인(aa 1-455)을 인식하며, 크로마틴 조절 및 전사 억제 연구에 활용 가능.
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Thermo Fisher Scientific SFMBT1 Recombinant Human Monoclonal Antibody (RAB-C396)
Applications
- ELISA (ELISA): Assay-dependent
- ChIP assay (ChIP): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Human / F(ab), kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | RAB-C396 |
| Immunogen | Recombinant antibody (rAb) phage display recognizing SFMBT1 protein under non-denaturing conditions |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Metal-chelate chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
Product Specific Information
This antibody recognizes SFMBT1 (Scm-like with four MBT domains protein 1).
It binds to a folded domain corresponding to amino acids 1–455.
SFMBT1 is a histone-binding protein that participates in various corepressor complexes.
It mediates recruitment of these complexes to target genes, leading to chromatin compaction and transcriptional repression, and plays a role during myogenesis.
Target Information
The SFMBT1 gene shares high similarity with the Drosophila Scm (sex comb on midleg) gene.
It encodes a protein containing four malignant brain tumor repeat (MBT) domains, potentially involved in antigen recognition.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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