Thermo Fisher Scientific SEMA3E Polyclonal Antibody
SEMA3E 단백질을 인식하는 토끼 폴리클로날 항체로, Human, Mouse, Rat 시료에 반응합니다. Western blot에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 고순도(>95%) 제품으로 연구용에 적합합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
- View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues in Human SEMA3E |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719412 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is greater than 95% as determined by SDS-PAGE.
Target Information
Semaphorins constitute the largest family of axon guidance cues described to date. They are divided into eight classes (classes 3–7 found in vertebrates):
- Class 3 Semaphorins: Secreted proteins
- Classes 4–6: Transmembrane proteins
- Class 7: Membrane-associated via glycosylphosphatidylinositol (GPI) linkage
Semaphorins are characterized by a conserved ~400 amino acid sema domain. Traditionally known as collapsing factors and mediators of axon repulsion, they can also function as context-dependent chemoattractants. They play roles in cardiovascular development and immune cell antigen presentation. Receptors mediating semaphorin signaling include members of the Neuropilin and Plexin families.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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