Thermo Fisher Scientific SLUG Polyclonal Antibody
Rabbit polyclonal antibody recognizing human SLUG protein. Validated for Western blot at 1:500–1:1,000 dilution. Affinity-purified with >95% purity. Suitable for EMT and transcription factor studies. For research use only.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific SLUG Polyclonal Antibody
Applications
- Western Blot (WB): 1:500–1:1,000 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues in Human SLUG |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719409 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. Purity is greater than 95% as determined by SDS-PAGE.
Target Information
Slug is a member of the Snail family of C2H2-type zinc finger transcription factors. It plays a role in epithelial-mesenchymal transition (EMT) and neural tube formation during vertebrate embryogenesis. Slug transcription can be induced by growth factors such as FGF, BMP, and TGF-beta. Once expressed, Slug binds E-box regions of promoters and represses transcription of genes such as E-cadherin and Claudin-1. Its expression in breast, esophageal, and colorectal carcinomas has been correlated with poor prognosis. Slug also protects hematopoietic progenitor cells from radiation-induced apoptosis by repressing p53-mediated transcription of Puma, a BH3-only antagonist of anti-apoptotic Bcl-2 family members.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.