Thermo Fisher Scientific REEP1/REEP2 Monoclonal Antibody (S326D-29)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

-

Immunohistochemistry (PFA fixed) (IHC (PFA))

1:50

-

Immunocytochemistry (ICC/IF)

Assay-Dependent

-

Product Specifications

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

S326D-29

Immunogen

Fusion protein amino acids 111-254 (Cytoplasmic C-terminus) of mouse REEP2.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2735344

Target Information

The REEP family are transmembrane proteins that interact with odorant receptor proteins and may enhance the odorant receptor responses to odorants. REEP2 is an integral membrane protein expressed in taste cells. Unlike its counterpart REEP1, REEP2 does not increase cell surface expression to sweet receptors, but instead alters their spatial organization. REEP1 protein is a mitochondrial protein that functions to enhance the cell surface expression of odorant receptors. Mutations in the REEP1 gene cause spastic paraplegia autosomal dominant type 31, a neurodegenerative disorder.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.