Thermo Fisher Scientific TRPM7 Monoclonal Antibody (S74)
TRPM7 단백질을 인식하는 S74 클론 단일클론 항체로, 인간·마우스·랫트에서 반응합니다. Western blot, IHC, ICC/IF 등 다양한 분석에 적합하며, 비결합형 액상 형태로 제공됩니다. 고순도 Protein G 정제, 안정적인 PBS/glycerol 버퍼 보존.
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- pk
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Thermo Fisher Scientific TRPM7 Monoclonal Antibody (S74)
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | - |
| Immunohistochemistry (IHC) | - | 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000 | - |
| Immunocytochemistry (ICC/IF) | 1:100 | 1 publication |
| Immunoprecipitation (IP) | - | 1 publication |
| Antibody Microarray (AM) | Assay-dependent | - |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse, Pig, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | S74 |
| Immunogen | Fusion protein amino acids 1817–1863 (C-terminus) of mouse TrpM7 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2735401 |
Additional Formats
Product Specific Information
1 µg/mL of MA5-27620 was sufficient for detection of TrpM7 in 10 µg of COS cell lysate transiently transfected with TrpM7 by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
Detects approximately 220 kDa in extracts of cells transiently transfected with TrpM7. No cross-reactivity against TrpM6.
Target Information
TRPCs, mammalian homologs of the Drosophila transient receptor potential (trp) protein, are ion channels that mediate capacitative calcium entry into the cell.
TRP-PLIK is a protein that functions as both an ion channel and a kinase. As a channel, it conducts calcium and monovalent cations to depolarize cells and increase intracellular calcium. As a kinase, it phosphorylates itself and other substrates. The kinase activity is essential for channel function, as shown by its dependence on intracellular ATP and by kinase mutants.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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