Thermo Fisher Scientific NLGN3 Monoclonal Antibody (N110/29)
NLGN3 단백질을 인식하는 Mouse monoclonal antibody (Clone N110/29). Western blot, IHC, ICC/IF에 사용 가능하며 Neuroligin-1, -2, -4와 교차 반응 없음. 단백질 G 정제, PBS/glycerol buffer, -20°C 보관.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1:100 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | N110/29 |
| Immunogen | Fusion protein amino acids 730–848 (intracellular C-terminus) of rat Neuroligin-3. Mouse: 99% identity (118/119 aa identical). Human: 98% identity (116/119 aa identical). ~60% identity with Neuroligin-1; ~40% with Neuroligin-2. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.1% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2735291 |
Additional Formats
Product Specific Information
1 µg/mL of MA5-27621 was sufficient for detection of Neuroligin 3 in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. Detects approximately 110 kDa.
Does not cross-react with Neuroligin-1, -2, -4 or -4.
This antibody was formerly sold as clone S110-29.
Target Information
This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses.
Mutations in this gene may be associated with autism and Asperger syndrome.
Multiple transcript variants encoding distinct isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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