Thermo Fisher Scientific Phospho-Rad52 (Tyr104) Polyclonal Antibody
RAD52 단백질의 Tyr104 인산화 형태를 특이적으로 검출하는 폴리클로날 항체. Western blot에 적합하며, 인간과 생쥐 시료에서 반응. 고순도 정제, PBS/glycerol 저장액, -20°C 보관. 연구용으로 DNA 복구 메커니즘 분석에 활용 가능.
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Thermo Fisher Scientific Phospho-Rad52 (Tyr104) Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human RAD52 (Accession P43351), corresponding to amino acid residues around phosphorylated Tyr104 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816645 |
Product Specific Information
Antibody detects endogenous levels of RAD52 only when phosphorylated at Tyr104.
Target Information
DNA double-strand breaks can be generated by exposure to ionizing radiation or through endogenous cellular reactions.
Double-strand breaks are generally repaired via two mechanisms: homologous recombination (HR) or non-homologous end joining (NHEJ).
Homologous recombination requires the activity of the RAD52 epistasis group, which includes RAD50, RAD51, RAD52, RAD54, RDH54/TID1, RAD55, RAD57, RAD59, MRE11, and XRS2.
RAD52 catalyzes strand annealing reactions and can form oligomers that attach to ends of single-stranded DNA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: PA5-105172_RAD52_P43351-1_Rabbit.svg)
(이미지: PA5-105172_RAD52_P43351-1_Rabbit_PDP.jpeg)
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