Thermo Fisher Scientific Aquaporin 0 Polyclonal Antibody
Aquaporin 0 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에 적합하며 Human, Mouse, Rat에서 반응. 고순도 항원 친화 크로마토그래피 정제, Lyophilized 형태로 제공. 연구용으로만 사용.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 0.1–0.5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to a sequence at the C-terminus of mouse Aquaporin 0 (246–263aa NGQPEGTGEPVELKTQAL) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5 mg BSA |
| Contains | 0.05 mg sodium azide, 0.05 mg thimerosal |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2746788 |
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
AQP0 is the most abundant endogenous protein in the plasma membrane of lens fiber cells. It functions as a water pore and is involved in fiber-fiber adhesion, essential for fiber cell structure and organization.
AQP0 has a unique pore constriction responsible for gating; its closed pore holds three water molecules spaced too far apart to form hydrogen bonds.
The C-terminal domain undergoes extensive post-translational modifications, including truncations during lens aging, which may contribute to cataract development.
주의사항
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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