Thermo Fisher Scientific Aquaporin 0 Polyclonal Antibody
Aquaporin 0 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot에 적합하며 인간과 랫트 시료에 반응. 항원 친화 크로마토그래피로 정제된 비결합 항체로, 렌즈 섬유 세포 연구에 활용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 0.1–0.5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to a sequence at the C-terminus of human Aquaporin 0 (232–263aa ERLSVLKGAKPDVSNGQPEVTGEPVELNTQAL) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS with 5 mg BSA |
| Contains | 0.05 mg sodium azide |
| Storage conditions | −20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2746789 |
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
AQP0 is the most abundant endogenous protein in the plasma membrane of lens fiber cells. It functions as a water pore and is involved in fiber-fiber adhesion, crucial for lens fiber cell structure and organization.
AQP0 has a unique pore constriction responsible for pore gating. The closed AQP0 pore contains three water molecules spaced too far apart to form hydrogen bonds.
Its C-terminal domain undergoes extensive post-translational modifications, including truncations during lens aging, which may contribute to cataract development.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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