Thermo Fisher Scientific OTX2 Monoclonal Antibody (1H12G8B2)
OTX2 단백질을 검출하기 위한 Thermo Fisher Scientific의 Mouse Monoclonal Antibody. Western blot, IHC, ICC/IF, ELISA 등 다양한 응용에 적합. Human, Mouse, Rat 시료에 반응하며, 비결합형 액상 형태로 제공. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:200–1:1,000 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1H12G8B2 |
| Immunogen | Purified recombinant fragment of human OTX2 expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_11153974 |
Product Specific Information
MA5-15855 targets OTX2 in indirect ELISA, IF, IHC, and WB applications and shows reactivity with Human samples.
The immunogen is a purified recombinant fragment of human OTX2 expressed in E. coli.
MA5-15855 detects OTX2, which has a predicted molecular weight of approximately 32 kDa.
Target Information
OTX2 is a 289-amino-acid protein belonging to the bicoid sub-family of homeodomain-containing transcription factors.
It has two known alternative splice variants with distinct isoforms, though other isoforms cannot be excluded.
OTX2 is an early marker of endodermal differentiation of embryonic stem cells and may play a role in brain and sensory organ development.
The protein may bind to the BCD target sequence (BTS): 5'-TCTAATCCC-3'.
Defects in OTX2 are associated with microphthalmia syndromic type 5 (MCOPS5).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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