Thermo Fisher Scientific OTX2 Monoclonal Antibody (1H12C4B5)
OTX2 단백질을 인식하는 Thermo Fisher Scientific의 Mouse Monoclonal Antibody입니다. Western blot, IHC, ICC/IF, Flow cytometry, ELISA 등 다양한 응용에 사용 가능하며 Human, Mouse, Rat 시료에 반응합니다. 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | - |
| Immunohistochemistry (IHC) | - | View 5 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 | - |
| Immunocytochemistry (ICC/IF) | 1:200–1:1,000 | - |
| Flow Cytometry (Flow) | 1:200–1:400 | - |
| ELISA | 1:10,000 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human, Mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1H12C4B5 |
| Immunogen | Purified recombinant fragment of human OTX2 expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C and avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11155193 |
Product Specific Information
MA5-15854 targets OTX2 in indirect ELISA, FACS, IF, IHC, and WB applications and shows reactivity with Human samples.
The immunogen is a purified recombinant fragment of human OTX2 expressed in E. coli.
MA5-15854 detects OTX2, which has a predicted molecular weight of approximately 32 kDa.
Target Information
OTX2 is a 289 amino acid protein belonging to the bicoid sub-family of homeodomain-containing transcription factors.
It has two known alternative splice variants with distinct isoforms, though additional isoforms may exist.
OTX2 is an early marker of endodermal differentiation of embryonic stem cells and plays a role in brain and sensory organ development.
It may bind to the BCD target sequence (BTS): 5-TCTAATCCC-3.
Defects in OTX2 are associated with microphthalmia syndromic type 5 (MCOPS5).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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