Thermo Fisher Scientific Phospho-PAK1 (Thr212) Polyclonal Antibody
PAK1 Thr212 인산화 형태를 특이적으로 인식하는 Rabbit Polyclonal 항체. Western blot, IHC, ICC 등 다양한 응용에 적합. Human, Mouse, Rat 시료에 반응하며, 순차 크로마토그래피로 정제된 고순도 제품. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | View 2 publications |
| Immunohistochemistry (IHC) | – | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | – |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 | – |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human PAK1 (Accession Q13153), corresponding to amino acid residues around phosphorylated Thr212. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816456 |
Product Specific Information
This antibody detects endogenous levels of PAK1 only when phosphorylated at Threonine 212.
Target Information
PAK1 is a serine/threonine kinase that serves as a target for restenosis, cancer, and immunosuppression treatment. It interacts with small GTP-binding proteins Cdc42 and Rac, and is involved in regulating diverse biological activities such as cell motility and morphology.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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