Thermo Fisher Scientific Lyn Polyclonal Antibody
Human 및 Mouse에 반응하는 Rabbit Polyclonal Lyn 항체로, WB, IHC, ICC/IF에 사용 가능. 고순도 항원 친화 크로마토그래피 정제, 0.86 mg/mL 농도, 액상 형태. 세포 신호전달 및 B세포 수용체 연구에 적합.
- 카탈로그번호
- PA529329
- 판매단위
- pk
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Thermo Fisher Scientific Lyn Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 152–450 of Human LYN |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.86 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2546805 |
Product Specific Information
- Recommended positive controls: A431, mouse brain, K562
- Predicted reactivity: Mouse (98%), Rat (97%), Zebrafish (85%), Xenopus laevis (90%), Chicken (92%), Sheep (99%), Bovine (99%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Lyn proto oncogene (Lcl/Yes related novel protein tyrosine kinase) is encoded by the Lyn gene located on chromosome 8 in humans and belongs to the Src family kinase. It is a non-receptor tyrosine kinase that acts as a mediator in transducing cellular signaling. Lyn is primarily expressed in hematopoietic cell types, including lymphoid and myeloid cells, but not in T lymphocytes. It plays diverse roles such as regulation of B cell receptor signaling, mast cell signaling, and Epithelial-Mesenchymal Transition (EMT).
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: PA5-29329_Lyn_P07948-1_Rabbit.svg, PA5-29329_Lyn_P07948-1_Rabbit_PDP.jpeg)
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