Thermo Fisher Scientific Phospho-PDE11A (Ser163) Polyclonal Antibody, Biotin
Phospho-PDE11A (Ser163) 인산화 부위를 인식하는 Biotin 결합 폴리클로날 항체입니다. Western blot, ELISA, Immunoprecipitation 등 다양한 분석에 사용 가능하며, Human, Mouse, Rat에서 반응합니다. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공합니다.
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Thermo Fisher Scientific Phospho-PDE11A (Ser163) Polyclonal Antibody, Biotin
Applications 및 권장 희석 배수
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:5,000 |
| ELISA | 1:50,000 |
| Immunoprecipitation (IP) | 1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 100–200 on rat PDE11A protein, phosphorylated at Ser163 |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5–1.5 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Proprietary buffer with 30% glycerol |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
3’,5’-cyclic nucleotides cAMP and cGMP act as second messengers in diverse signaling pathways. 3’,5’-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to their corresponding 5’-monophosphates, thereby downregulating signal transduction. The PDE11A gene encodes a member of the PDE superfamily. Mutations in this gene are associated with Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: PPD11A-170-BIOTIN_PDE11A_Q8VID6-1_Rabbit.svg, PPD11A-170-BIOTIN_PDE11A_Q8VID6-1_Rabbit_PDP.jpeg)
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