Thermo Fisher Scientific Phospho-PDE11A (Ser162) Polyclonal Antibody
PDE11A 단백질의 Ser162 인산화 부위를 인식하는 Rabbit Polyclonal 항체로, Western blot, ELISA, IP에 적합합니다. 높은 특이성과 안정성을 제공하며, 연구용으로만 사용됩니다.
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Thermo Fisher Scientific Phospho-PDE11A (Ser162) Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 100–150 on PDE11A protein, phosphorylated at Ser117 & Ser124 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer (pH 7.4–7.8) with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
3’,5’-cyclic nucleotides cAMP and cGMP act as second messengers in diverse signal transduction pathways. 3’,5’-cyclic nucleotide phosphodiesterases (PDEs) hydrolyze cAMP and cGMP to their 5’-monophosphates, regulating cyclic nucleotide signaling. The PDE11A gene encodes a member of the PDE protein superfamily. Mutations in this gene are associated with Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been identified.
Usage Notes
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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