Thermo Fisher Scientific PIG3 Polyclonal Antibody
Rabbit polyclonal antibody targeting Human PIG3 (aa 230–286). Validated for Western blot at 1:500–1:1,000 dilution. Affinity-purified with >95% purity. Suitable for oxidative stress and p53 pathway research. For research use only.
- 판매단위
- pk
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Applications
- Western Blot (WB): 1:500–1:1,000 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 230–286 of Human PIG3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2718985 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is >95% as determined by SDS-PAGE.
Target Information
The protein encoded by the PIG3 gene is similar to oxidoreductases, enzymes involved in cellular responses to oxidative stress and irradiation. This gene is induced by the tumor suppressor p53 and is thought to participate in p53-mediated cell death.
It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 transcriptionally activates this gene through interaction with the microsatellite, which is polymorphic and correlates with transcriptional activation strength.
This polymorphism may influence cancer susceptibility. At least two transcript variants encoding the same protein have been identified.
For Research Use Only. Not for use in diagnostic procedures or resale without express authorization.
제품 이미지
(PA5-75257_PIG3_Q53FA7-1_Rabbit.svg 및 PA5-75257_PIG3_Q53FA7-1_Rabbit_PDP.jpeg 이미지 포함)
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