Thermo Fisher Scientific MRPS11 Monoclonal Antibody (OTI3B1), TrueMAB

Thermo Fisher Scientific MRPS11 Monoclonal Antibody (OTI3B1), TrueMAB

Applications

• Western Blot (WB)

Tested Dilution: 1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of about 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and assist in mitochondrial protein synthesis.
Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit, with approximately 75% protein to rRNA ratio—opposite to prokaryotic ribosomes.
Unlike prokaryotic ribosomes, mammalian mitoribosomes lack 5S rRNA.
The MRPS11 gene encodes a 28S subunit protein with high sequence similarity to ribosomal protein S11P family members.
A pseudogene exists on chromosome 20, and multiple transcript variants encoding different isoforms have been identified.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.