Thermo Fisher Scientific Phospho-JNK1/JNK2 (Thr183, Tyr185) Monoclonal Antibody (R.532.8)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

-

Product Specifications

Species Reactivity

Hamster, Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Monoclonal

Type

Antibody

Clone

R.532.8

Immunogen

Synthetic phosphopeptide corresponding to residues surrounding pThr183/Tyr185 of human SAPK/JNK if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:JNK1/JNK2,uniProtId:P45983-1,ncbiNodeId:9606,antigenRange:183|185,antigenLength:427,antigenImageFileName:MA5-15175_JNK1JNK2_P45983-1_Rabbit.svg,antigenImageFileNamePDP:MA5-15175_JNK1JNK2_P45983-1_Rabbit_PDP.jpeg,sortOrder:1},{targetFamily:JNK1/JNK2,uniProtId:P45984-1,ncbiNodeId:9606,antigenRange:183|185,antigenLength:424,antigenImageFileName:MA5-15175_JNK1JNK2_P45984-1_Rabbit.svg,antigenImageFileNamePDP:MA5-15175_JNK1JNK2_P45984-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

270 µg/mL

Purification

Affinity chromatography

Storage buffer

0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol

Contains

<0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_10986207

Product Specific Information

It is not recommended to aliquot this antibody.

Target Information

C-Jun N-terminal Kinase (JNK) is also known as Mitogen-activated protein kinase (MAPK8). It belongs to the MAPK superfamily of stress-activated protein kinases. MAPKs are Serine-threonine protein kinases that are activated in response to a variety of extracellular stimuli, and mediate signal transduction from the cell surface to the nucleus. JNK is involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. JNK pathways are activated by stress and inflammatory signals. JNK is expressed as ten different isoforms due to differential mRNA splicing. The predominant forms are JNK1 and JNK2.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.