Thermo Fisher Scientific NDUFA13 Recombinant Rabbit Monoclonal Antibody (ARC0833)
Thermo Fisher의 NDUFA13(ARC0833) 재조합 토끼 단클론 항체로, 인간 NDUFA13/GRIM19 단백질을 인식합니다. Western blot과 ELISA에 최적화되어 있으며, 고순도 친화 크로마토그래피 정제 제품입니다. 연구용으로만 사용 가능합니다.
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- MA535402
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- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC0833 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–144 of human NDUFA13/GRIM19 (Q9P0J0) (NP_057049.5) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.7 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849303 |
Product Specific Information
Immunogen sequence:
MAASKVKQDM PPPGGYGPID YKRNLPRRGL SGYSMLAIGI GTLIYGHWSI MKWNRERRRL QIEDFEARIA LLPLLQAETD RRTLQMLREN LEEEAIIMKD VPDWKVGESV FHTTRWVPPL IGELYGLRTT EEALHASHGF MWYT
Target Information
A novel gene associated with Retinoid-IFN-induced Mortality (GRIM) GRIM-19 gene was identified.
Antisense expression of GRIM-19 confers a strong resistance against IFN/RA-induced death by reducing the intracellular levels of GRIM-19 protein.
Overexpression of GRIM-19 enhances cell death in response to IFN/RA.
GRIM-19 is primarily a nuclear protein whose expression is induced by the IFN/RA combination.
These data indicate that GRIM-19 is a novel cell death-regulatory molecule.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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