Thermo Fisher Scientific Phospho-BLNK (Tyr84) Recombinant Rabbit Monoclonal Antibody (BLNKY84-H4)
인간 BLNK 단백질의 Tyr84 인산화 부위를 인식하는 재조합 토끼 단일클론 항체입니다. 높은 특이성과 민감도를 제공하며, Flow Cytometry에 최적화되어 있습니다. 로트 간 일관성과 동물 유래 성분이 없는 포뮬레이션을 제공합니다. 연구용으로만 사용 가능합니다.
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Applications
Flow Cytometry (Flow)
- Tested Dilution: 1–1,000 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | BLNKY84-H4 |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Tyr84 of human phospho BLNK |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745013 |
Additional Formats
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences from immunoreactive rabbits are cloned and screened to select optimal clones for production.
Advantages include:
- Improved specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broad immunoreactivity due to the rabbit immune repertoire
Target Information
B cell linker protein (BLNK), also known as SLP-65, is encoded by the BLNK gene on human chromosome 10. It functions as an adaptor protein in the B cell receptor signaling cascade. Phosphorylation of BLNK by Syk kinase enables interaction with signaling intermediaries such as Vav GEF and Grb2. Deficiency of BLNK can lead to improper B cell development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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