Thermo Fisher Scientific Phospho-4EBP1 (Thr37, Thr46) Recombinant Rabbit Monoclonal Antibody (4EB1T37T46-A5), PE
Phospho-4EBP1 (Thr37, Thr46) 인산화 단백질을 검출하는 PE-conjugated recombinant rabbit monoclonal antibody. 인간, 마우스, 랫트 시료에 반응하며 Flow Cytometry에 적합. 높은 특이성과 재현성을 제공하며, lot 간 일관성이 우수함.
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Applications
Flow Cytometry (Flow)
- Tested Dilution: 5 µL / 1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 4EB1T37T46-A5 |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Thr37/46 of human phospho 4E-BP1 |
| Conjugate | PE |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.2% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745011 |
Additional Formats
- Unconjugated (MA5-36935)
- APC (MA5-36938)
- FITC (MA5-36937)
- Custom conjugation available upon request
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. Antibody DNA sequences from immunoreactive rabbits are cloned and screened to select optimal clones for production.
These antibodies offer:
- Enhanced specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to the rabbit immune repertoire
Target Information
This gene encodes a translation repressor protein that interacts with eukaryotic translation initiation factor 4E (eIF4E), a key component in recruiting 40S ribosomal subunits to mRNA.
Phosphorylation of this protein (e.g., by UV or insulin signaling) causes dissociation from eIF4E, enabling translation activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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