Thermo Fisher Scientific CD5 Recombinant Rabbit Monoclonal Antibody (114)
마우스 CD5 단백질을 인식하는 재조합 토끼 단클론 항체로 높은 특이성과 재현성을 제공합니다. ICC/IF 및 유세포분석에 적합하며, 보존제가 없는 액상 형태입니다. Protein A로 정제되었으며 4°C 또는 -20°C에서 보관 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 1:20–1:100 |
| Flow Cytometry (Flow) | 1:25–1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 114 |
| Immunogen | Recombinant Mouse CD5/Cluster of Differentiation 5 protein (Met1–Pro371) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2785502 |
Additional Conjugate Formats
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.
Advantages of recombinant rabbit monoclonal antibodies:
- Better specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broad immunoreactivity due to large rabbit immune repertoire
This antibody specifically recognizes Mouse CD5/Cluster of Differentiation 5.
Target Information
CD5 is a 67 kDa human T-lymphocyte single-chain transmembrane glycoprotein. It is expressed on all mature T-lymphocytes, most thymocytes, and many T-cell leukemias and lymphomas. CD5 also reacts with a subpopulation of activated B-cells and may act as a receptor regulating T-cell proliferation.
CD5 is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, reactivity is mainly observed in T cell areas. CD5 expression is associated with T cell leukemia, lymphomas, and activated T cells.
Diseases associated with CD5 dysfunction include thymus cancer and Richter’s Syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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