Thermo Fisher Scientific CD55 Recombinant Rabbit Monoclonal Antibody (076)
Thermo Fisher Scientific의 CD55 Recombinant Rabbit Monoclonal Antibody (Clone 076)은 Mouse CD55/DAF 단백질을 특이적으로 인식하는 고감도 항체입니다. ICC/IF 및 Flow Cytometry에 적합하며, preservative-free 포맷으로 제공됩니다. 재조합 기술로 높은 재현성과 특이성을 보장합니다.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:20–1:100
Flow Cytometry (Flow)
- Tested Dilution: 1:25–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 076 |
| Immunogen | Recombinant Mouse CD55/DAF Protein (Met1–Thr361) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2785504 |
Additional Formats
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.
Advantages of recombinant rabbit monoclonal antibodies:
- Better specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to larger rabbit immune repertoire
This antibody has specificity for Mouse CD55/DAF.
Target Information
CD55 (decay-accelerating factor, DAF) is a GPI-anchored membrane glycoprotein that protects autologous cells from the classical and alternative complement pathways. Interactions between CD55 and CD97 are involved in T-cell regulation, and CD55 can regulate complement when bound to CD97.
In tumors, CD55 promotes neoangiogenesis, tumorigenesis, invasiveness, and evasion of apoptosis. CD55 is a 70 kDa glycoprotein anchored by a glycosylphosphatidylinositol tail. It binds to activated C4b or C3b complement fragments on the cell surface, preventing assembly and accelerating decay of complement pathways.
CD55 carries Cromer-related blood group antigens. Two alternatively spliced transcripts encode CD55: one for a membrane-bound protein and another for a soluble form expressed at lower levels. CD55 has been studied for its role in prostate cancer growth and survival.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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