Thermo Fisher Scientific MyoD1 Polyclonal Antibody
MyoD1 단백질을 인식하는 Rabbit Polyclonal 항체로, WB 및 IHC(P) 실험에 적합합니다. Human, Mouse, Rat 시료에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide (EHY SGD SDA SSP RSN) corresponding to human MyoD1 (amino acids 191–205) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C (short term); -20°C (long term). Avoid freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: Rhabdomyosarcoma tissue
- Cellular location: Nucleus
Target Information
The Myogenic determination gene (MyoD) was first identified by its ability to convert embryonic mouse fibroblast cells into muscle cells. Forced expression of the MyoD (human homolog: myf3) gene in various cell types can induce muscle cell characteristics or activate muscle-specific genes.
The regulatory domain of MyoD includes a 70-amino-acid region containing a basic DNA-binding motif and a helix-loop-helix (HLH) dimerization motif.
Related genes sharing homology with MyoD include myf5, myogenin (myf4), and myf6 (MRF4/herculin).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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