Thermo Fisher Scientific Cytokeratin 14 (KRT14) (Squamous Cell Marker) Recombinant Rabbit Monoclonal Antibody (KRT14/7977R)
인간 Cytokeratin 14(KRT14)을 인식하는 재조합 토끼 단클론 항체로, 편평상피세포 표지에 사용. IHC(P) 및 IHC(PFA) 적용 가능. HEK293 세포에서 발현된 IgG 항체이며, 단백질 A/G로 정제된 액상 형태. 연구용으로만 사용.
- 카탈로그번호
- 3861RBM37P1ABX
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific Cytokeratin 14 (KRT14) (Squamous Cell Marker) Recombinant Rabbit Monoclonal Antibody (KRT14/7977R)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | KRT14/7977R |
| Immunogen | Recombinant human KRT14 fragment (around aa272–472) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Target Information
Cytokeratins (CK) are intermediate filaments found in epithelial cells, both keratinizing (e.g., skin) and non-keratinizing (e.g., mesothelial) tissues. There are at least 20 different CKs, classified into type I (acidic polypeptides) and type II (basic polypeptides).
Keratin 14, a type I low molecular weight keratin, forms a complex with keratin 5 and helps distinguish stratified epithelial cells from simple epithelial cells. It is useful for identifying squamous cell carcinomas and is considered a prognostic marker in breast carcinomas.
At least one acidic and one basic keratin are expressed in all epithelial cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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