Thermo Fisher Scientific NMDAR1 Monoclonal Antibody (R1JHL)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

View 3 publications 3 publications

Immunohistochemistry (IHC)

1:400-1:1,000

-

Immunocytochemistry (ICC/IF)

1:10

View 1 publication 1 publication

Immunoprecipitation (IP)

3 µg/200 µg lysate

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Mouse, Rat

Host/Isotype

Mouse

Class

Monoclonal

Type

Antibody

Clone

R1JHL

Immunogen

Fusion protein containing amino acids 1-564 of the NR1 subunit of rat GRIN1 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:NMDAR1,uniProtId:P35439-1,ncbiNodeId:10114,antigenRange:1-938,antigenLength:938,antigenImageFileName:OMA1-04010_NMDAR1_P35439-1_House_mouse.svg,antigenImageFileNamePDP:OMA1-04010_NMDAR1_P35439-1_House_mouse_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

Conc. Not Determined

Storage buffer

tissue culture supernatant, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_325527

Product Specific Information

In Western blot, this antibody detects a single ~120 kDa protein representing NR1 in rat brain homogenate. It shows no cross-reactivity with any of the NR2 subunits.

Reconstitute with 50 µL of PBS.

Target Information

NMDAR1 encodes a protein that is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.