Thermo Fisher Scientific Factor V Monoclonal Antibody (5102)

Applications

Tested Dilution

Publications

Western Blot (WB)

5 µg/mL

-

Radioimmune Assays (RIA)

5-10 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG

Class

Monoclonal

Type

Antibody

Clone

5102

Immunogen

120kD activation peptide of human factor V.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Purification

SDS-PAGE

Storage buffer

50% water with 50% glycerol

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_1074323

Product Specific Information

MA1-43001 detects Factor V in human samples.

MA1-43001 has successfully been used in RIA and Western blot applications.

MA1-43001 was derived from the 120kD activation peptide of human factor V.

Target Information

Coagulation factor V (or Proaccelerin) is an essential factor of the blood coagulation cascade. This factor circulates in plasma, and is converted to the active form by the release of the activation peptide by thrombin during coagulation. This generates a heavy chain and a light chain which are held together by calcium ions. The active factor V is a cofactor that participates with activated coagulation factor X to activate prothrombin to thrombin. Defects in the Factor V gene can result various diseases including Factor V deficiency, thrombophilia due to activated protein C resistance, Budd-Chiari syndrome, Ischemic stroke, and recurrent pregnancy loss.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.