Thermo Fisher Scientific Phospho-TLR4 (Ser800) Polyclonal Antibody
TLR4의 Ser800 인산화 형태를 특이적으로 검출하는 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF 등 다양한 응용 가능. 인간, 생쥐, 랫드 반응성. 고순도 액상 형태로 -20°C 보관.
✨AI 추천 연관 상품
AI가 분석한 이 상품과 연관된 추천 상품들을 확인해보세요
연관 상품을 찾고 있습니다...
Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human TLR4 (Accession O00206), corresponding to amino acid residues around phosphorylated Ser800 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2817141 |
Product Specific Information
This antibody detects endogenous levels of TLR4 only when phosphorylated at Ser800.
Target Information
TLR4 is a member of the Toll-like receptor (TLR) family, playing a fundamental role in pathogen recognition and activation of innate immunity. TLRs are conserved across species and share structural and functional similarities. TLR4 is most abundantly expressed in the placenta and in myelomonocytic leukocytes. It is a key component of the lipopolysaccharide (LPS) receptor complex, along with CD14 and LY96, mediating signal transduction induced by LPS from gram-negative bacteria. TLR4 recognizes pathogen-associated molecular patterns (PAMPs) and triggers cytokine production necessary for effective immune responses. Mutations in the TLR4 gene can affect LPS responsiveness. The receptor is expressed in monocytes, some B-cells, and placenta. TLR4-deficient mice show increased susceptibility to Gram-negative sepsis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
🏷️Thermo Fisher Scientific 상품 둘러보기
동일 브랜드의 다른 상품들을 확인해보세요
Thermo Fisher Scientific
Thermo Fisher Scientific ARHGAP42 Polyclonal Antibody
627,600원
Thermo Fisher Scientific
Thermo Fisher Scientific BACH1 Polyclonal Antibody
627,600원
Thermo Fisher Scientific
Thermo Fisher Scientific Phospho-TLR4 (Ser800) Polyclonal Antibody
627,600원
Thermo Fisher Scientific
Thermo Fisher Scientific Phospho-RyR2 (Ser2808) Polyclonal Antibody
627,600원
Thermo Fisher Scientific
Thermo Fisher Scientific N-WASP Polyclonal Antibody
627,600원
배송/결제/교환/반품 안내
배송 정보
| 기본 배송비 |
| 교환/반품 배송비 |
|
|---|---|---|---|
| 착불 배송비 |
| ||
| 교환/반품 배송비 |
| ||
결제 및 환불 안내
| 결제수단 |
|
|---|---|
| 취소 |
|
| 반품 |
|
| 환급 |
|
교환 및 반품 접수
| 교환 및 반품 접수 기한 |
|
|---|---|
| 교환 및 반품 접수가 가능한 경우 |
|
| 교환 및 반품 접수가 불가능한 경우 |
|
교환 및 반품 신청
| 교환 절차 |
|
|---|---|
| 반품 절차 |
|