Thermo Fisher Scientific PRDX2 Polyclonal Antibody
PRDX2 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot에 적합하며 인간, 마우스, 랫트 시료에 반응. 항원 친화 크로마토그래피로 정제된 리오필라이즈 형태. 세포 증식 및 산화 스트레스 연구용으로 적합.
- 카탈로그번호
- PA579862
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 0.1–0.5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to a sequence at the C-terminus of human Peroxiredoxin 2 (181–198 aa: DTIKPNVDDSKEYFSKHN) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS with 5 mg BSA |
| Contains | 0.05 mg sodium azide, 0.05 mg thimerosal |
| Storage conditions | -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2746977 |
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
Peroxiredoxin (Prx) is a peroxidase family involved in cell proliferation, differentiation, and apoptosis. Mammalian Prx consists of six members categorized as typical 2-Cys, atypical 2-Cys, and 1-Cys Prx.
Except for Prx VI (1-Cys subgroup), the other five 2-Cys Prx isotypes have thioredoxin-dependent peroxidase (TPx) activity utilizing thioredoxin, thioredoxin reductase, and NADPH as a reducing system.
Mammalian Prxs (20–30 kDa) vary in subcellular localization:
- Prx I, II, VI: Cytosol
- Prx III: Mitochondria
- Prx IV: ER and secretion
- Prx V: Peroxisome, mitochondria, and cytosol
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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