Thermo Fisher Scientific GABRG2 Polyclonal Antibody
GABRG2 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC에 적합합니다. Mouse와 Rat에 반응하며, GABA-A receptor gamma 2 단백질 검출에 사용됩니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (IHC) | 1:400 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acid residues specific to the gamma 2 subunit of rat GABRG2 conjugated to KLH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Storage buffer | Whole serum |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_325317 |
Product Specific Information
This antibody is predicted to react with chicken, human, mouse, non-human primate, and zebrafish based on 100% sequence homology.
The antigenic sequence has no homology with any other GABA-A receptor or alpha and beta subunits.
In Western blot, this antibody detects a ~45–47 kDa protein representing GABA-A receptor gamma 2 in rat brain membranes.
Target Information
This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain, acting at GABA-A receptors, which are ligand-gated chloride channels.
GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta, and rho.
Mutations in this gene have been associated with epilepsy and febrile seizures. Multiple transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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