Thermo Fisher Scientific mGluR2/mGluR3 Polyclonal Antibody
mGluR2/mGluR3 단백질을 인식하는 토끼 폴리클로날 항체로, WB 및 IHC에 적합합니다. 다양한 종과 교차 반응하며, 비스플라이스 변이체에는 반응하지 않습니다. 연구용으로만 사용 가능하며, -20°C에서 보관하십시오.
- 카탈로그번호
- OPA104061
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (IHC) | 1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the C-terminal region of rat GRM2/3 conjugated to KLH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2279541 |
Product Specific Information
This antibody is predicted to react with bovine, canine, human, mouse, non-human primate, and zebrafish based on 100% sequence homology.
It is specific to mGluR2/3 and does not cross-react with other splice variants.
Target Information
The mGluR proteins (metabotropic Glutamate Receptors) are members of the G-protein-coupled receptor family and are functionally and pharmacologically distinct from the GluR proteins (ionotropic Glutamate Receptors).
The eight currently known mGluR proteins are mediated by two G-proteins with opposing regulation of adenylate cyclase pathways.
The activities of mGluR1 and mGluR5 are mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current.
The remaining mGluR subtypes have activity mediated by a G-protein that inhibits adenylate cyclase activity.
mGluR-3, which may interact with GRASP, acts as a receptor for glutamate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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